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Biochemistry Manager

Company: Sema4
Location: Stamford
Posted on: September 14, 2020

Job Description:

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Sema4 is a patient-centered health intelligence company founded on the idea that more information, deeper analysis, and increased engagement will improve the diagnosis, treatment, and prevention of disease. Sema4 is dedicated to transforming healthcare by building dynamic models of human health and defining optimal, individualized health trajectories, starting in the areas of reproductive health and oncology. Centrellis™, our innovative health intelligence platform, is enabling us to generate a more complete understanding of disease and wellness and to provide science-driven solutions to the most pressing medical needs. Sema4 believes that patients should be treated as partners, and that data should be shared for the benefit of all.

Sema4 is seeking a Laboratory Operations Manager - Biochemistry/Functional Genomics Lab for a full-time position located in New York City with the primary responsibility to carry out, oversee, and manage operations in a clinical setting employing state of the art Mass Spectrometry, Flourometry, and HPLC technologies. The Laboratory Operations Manager will manage workflow on a day to day basis, as well as plan and execute projects as needed to advance business needs. The position requires technical as well as people management skills, with each Manager responsible for technical processes as well as the team performing the testing.

NOTE: this role will transition to our new Stamford, CT Clinical location in 2020.

RESPONSIBILITIES

Productivity and adherence to quality of the scientists in the clinical laboratory

Oversight of operations processes spanning specimen receipt, specimen preparation and processing, analytical processes, data analysis, QC review, and result interpretation

Leadership of the team includes the management of scheduling and staffing to meet productivity goals, modeling of best practices as a clinical laboratory scientist, and expert level technical supervision of lab processes.

Utilize a number of industry leading high throughput automation platforms, as well as classical manual methods and techniques, to obtain clinical results and to provide medical information to our patients and clients.

Techniques and technologies which will demand highly technically competent candidates and experts in their field.

Provide supervision to high complexity biochemistry testing of clinical samples from various tissues and biological sources such as whole blood, plasma, urine, cell culture samples, and others.

Provides guidance, training, and mentorship to technical and non-technical staff in the laboratory.

Able to support the laboratory processes in technical, operations, and regulatory topics to deliver results of the highest integrity in a laboratory fully compliant with all federal, state, and local regulations.

Ability to support, direct, and troubleshoot the preparation and processing of samples for Mass Spectrometric and Flourometric analysis, HPLC, data analysis and interpretation in a high-throughput clinical production laboratory employing state of the art liquid handling and automation systems.

Adheres to strict protocols and best practices required for clinical testing following CAP, CLIA, and NYSDOH regulations while maintaining all required records and documentation for continual inspection readiness.

Ensures the maintenance of lab supplies and consumables sufficient to meet productivity goals. Reviews the utilization of consumables and reagents to ensure efficiency. Works with lab leadership to develop and maintain financial models for department consumption.

Directs and oversees the creation, review, and maintenance of SOPs, forms, and lab documents in cooperation with lab leadership, quality assurance, and the clinical leadership teams.

QUALIFICATIONS

Bachelor’s Degree (B.A or B.S.) in Biology, Chemistry, Cell or Molecular Biology, Biochemistry, a degree as a Medical Laboratory Scientist, or another closely related field with sufficient credits to satisfy regulatory standards and at least one year of clinical laboratory experience.

An unofficial transcript will be required for domestic degrees and an equivalency will be required for foreign degrees with the submission of your resume to certify your degree and credit requirements.

Experience working in a high throughput commercial lab or clinical laboratory setting will be given preference.

Familiarity with and advanced understanding of physical wet-bench techniques such as automated liquid handling, biochemical extraction, HPLC, Mass Spectrometry (GC-MS/LC-MS), enzyme assays, flourometry, and the efficient us of high-throughput automation is absolutely required.

Minimum of 10+ years previous clinical laboratory work experience, or the relevant combination of advanced degree and experience, is required to fulfill regulatory requirements.

The ideal candidate has strong problem-solving, communication, and technological skills.

Must be a motivated team player willing to work in a fast-paced healthcare environment.

ASCP certification and state licensure is not required but is strongly desired.

Keywords: Sema4, Stamford , Biochemistry Manager, Other , Stamford, Connecticut

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